AOR Advanced Orthomolecular Research Premium Zinc-Copper Balance

Our assessment

The evidence shows that this product, AOR Advanced Orthomolecular Research Premium Zinc-Copper Balance, contains the ingredient calcium. Our assessment is that while calcium is essential for bone health, you need to be aware of specific safety concerns and potential medication interactions before starting this supplement.

How it works

Calcium works in your body primarily through bone mineralization, where it supports bone density and mineral deposition. It also plays a role in neuromuscular relaxation, supporting muscle relaxation and nerve signaling [NIH ODS].

Safety profile

Data not available for specific adverse events for this product. However, for calcium generally, some research suggests that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. The FDA has received a total of 592059 adverse event reports across all supplements [FDA data].

Our recommendation

We recommend that you speak with your healthcare provider before taking this supplement, especially if you take any medications. Calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Monitor your total calcium intake from all sources to avoid exceeding safe levels [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide