Natural Factors Stress-Relax Melatonin 3 mg
Brand: Natural Factors Stress-Relax · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that the ingredient calcium is well-established for bone health, but it does not address sleep or stress. For a product marketed as “Stress-Relax” with melatonin, the active sleep-support ingredient is melatonin, not calcium. Data on this specific product's effectiveness is not available.
How it works
Calcium acts as a master regulator for bone mineralization and neuromuscular relaxation, helping support bone density and nerve signaling [NIH ODS]. However, this mechanism is unrelated to the sleep-wake cycle. For stress-related sleep support, melatonin would be the key ingredient, but specific data on melatonin from this product is not available.
Safety profile
FDA has received a total of 592,059 adverse event reports across all dietary supplements. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can reduce the absorption of bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Based on the data provided, this product does not contain evidence-based ingredients for stress relief or relaxation. For sleep support, melatonin is a more direct option. If you are taking calcium for bone health, choose a dedicated calcium supplement and take it separately from other medications. Consult your pharmacist or doctor before starting any new supplement regimen.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Natural Factors Stress-Relax |
|---|---|
| Serving Size | |
| Contents | 90.0 Chewable Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide