ProEnzol Probiotic 5

Our assessment

The evidence shows that this product contains calcium, a mineral with strong support for bone health, but you should be aware of important safety considerations. Based on the data provided, calcium supports bone mineralization and neuromuscular function [NIH ODS]. However, we cannot assess the full effectiveness of the probiotic blend in this product because data on the specific probiotic strains is not available.

How it works

Think of calcium as a structural builder for your skeleton and a signal messenger for your nerves and muscles. It works by supporting bone density and mineral deposition, while also helping your muscles relax and your nerves send signals properly [NIH ODS]. The probiotic component’s mechanism is not detailed in the provided data.

Safety profile

FDA received a total of 592,059 adverse event reports across all supplements in the database, though specific counts for this product are not available. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer. High blood and urine levels of calcium can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

You should be cautious with this product if you take any of the medications listed above, as calcium can interfere with their absorption. Do not exceed recommended calcium intake levels without medical supervision. Because specific data on the probiotic strains is not available, we cannot confirm the digestive benefits of this formula. Your best approach is to discuss this product with your doctor or pharmacist, especially if you have a history of kidney problems, heart disease, or take prescription medications [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide