Cardiovascular Research Multiphasic Melatonin-SR 1.8 mg
Brand: Cardiovascular Research · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that the primary active ingredient in this product, calcium, is well-studied for bone health, but its role in cardiovascular health is more complex. Data not available on the specific formulation or brand name for this product.
How it works
Calcium supports bone mineralization and neuromuscular relaxation, meaning it helps your bones stay dense and your muscles and nerves function properly [NIH ODS]. For cardiovascular health, calcium plays a role in heart muscle contraction and nerve signaling, though the data on supplemental calcium for heart disease prevention is mixed [NIH ODS].
Safety profile
FDA received 592,059 adverse event reports across all products. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. Side effects from excessive calcium include poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Given the potential cardiovascular risks associated with high calcium intake, do not take this supplement without first consulting your healthcare provider. Get your calcium levels and heart health assessed before starting, especially if you take any of the listed medications [NIH ODS]. Data not available on a specific safe dose for this product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Cardiovascular Research |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide