Superior Source Melatonin 5 mg

Our assessment

The evidence shows that this product contains 5 mg of melatonin, a dose that is significantly higher than the typical starting dose of 0.5 to 1 mg. For general sleep support, you should be aware that high doses do not necessarily lead to better results and may increase the risk of side effects. Data for the specific ingredient calcium is provided, but melatonin-specific data from NIH ODS is not available for this report.

How it works

Melatonin is a hormone that regulates your sleep-wake cycle. While specific mechanism data for melatonin is not provided, the ingredient calcium works through bone mineralization, supporting bone density and mineral deposition, and neuromuscular relaxation, supporting muscle relaxation and nerve signaling [NIH ODS].

Safety profile

Data not available for melatonin-specific adverse events from the provided FDA data. The total FDA adverse event reports across all supplements is 592,059, but this number is not specific to this product or melatonin. For the ingredient calcium, high levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease. Some research also suggests high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS].

Our recommendation

We recommend starting with a lower dose of melatonin, typically 0.5 to 1 mg, taken 30-60 minutes before bed. Because this product provides 5 mg, you should be cautious and consider splitting the tablet if possible. Additionally, be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Consult with your healthcare provider before starting this supplement, especially if you take any medications or have a medical condition.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide