Applied Nutrition Rapid Sleep PM Extra 6 mg Melatonin
Brand: Applied Nutrition · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that this product contains 6 mg of melatonin per serving, which is a high dose. For calcium, the data indicates it supports bone mineralization and neuromuscular relaxation [NIH ODS]. However, you should be aware that supplementing with high levels of calcium may carry specific risks, including potential links to heart disease and prostate cancer [NIH ODS].
How it works
Think of calcium as a structural mineral — it is essential for bone density and mineral deposition, and it also supports muscle relaxation and nerve signaling [NIH ODS]. For the melatonin component of this product, data on its specific mechanism is not available from the provided sources.
Safety profile
The total adverse event reports for this brand and its ingredients in the FDA database is 592,059 [FDA data]. For calcium specifically, high intakes can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data on specific side effects for the melatonin component is not available.
Our recommendation
Given the high 6 mg melatonin dose and the potential risks associated with calcium, you should consult your doctor before starting this supplement. If you take any medications, especially those listed above, discuss potential interactions with your pharmacist or physician [NIH ODS]. Start with a lower melatonin dose if possible, and monitor for any side effects.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Applied Nutrition |
|---|---|
| Serving Size | |
| Contents | 40.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide