Product Label

Natural Factors Stress-Relax Melatonin 5 mg

Brand: Natural Factors Stress-Relax · Form: TABLET [E0155]

Our assessment

The evidence shows that this product contains 5 mg of melatonin per serving. Our assessment: for general sleep support, this is a dose that may be appropriate for some adults but is higher than the typical starting dose. Data on the specific ingredient melatonin is not provided in the data below, so we cannot offer a detailed analysis of its effects.

How it works

While specific data on melatonin is not available in the data provided, the included ingredient calcium works through bone mineralization to support bone density and through neuromuscular relaxation to support muscle relaxation and nerve signaling [NIH ODS].

Safety profile

For the product overall, FDA received 592,059 total adverse event reports across all products, but specific report counts for this product are not available. For the ingredient calcium, high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS].

Our recommendation

Because specific safety and efficacy data for melatonin is not provided, we cannot make a confident recommendation for this product. If you are considering a melatonin supplement, consult your healthcare provider to determine the appropriate dose for your needs. For the calcium component, be aware that it can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

AI-assisted analysis. Data sourced from NIH DSLD.

Supplement Facts

BrandNatural Factors Stress-Relax
Serving Size
Contents90.0 Chewable Tablet(s)
Market StatusOff Market

How to Read This Label

Supplement labels contain several key sections regulated by the FDA:

  • Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
  • Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
  • % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
  • Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
  • Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide

Original Label

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