Swanson Ultra Folate 5-Methyltetrahydrofolic Acid 800 mcg

Our assessment

The evidence shows that this product provides 800 mcg of folate in its active form, 5-MTHF, which is ready for your body to use. Data not available on specific benefits or efficacy for this exact product, but folate is essential for DNA synthesis and cell division.

How it works

Folate, as 5-MTHF, acts as a critical cofactor in your body's methylation cycle, which supports red blood cell formation and healthy homocysteine levels. Unlike folic acid, this form does not require conversion by the liver, making it ideal for individuals with MTHFR gene variations [NIH ODS].

Safety profile

FDA received 592,059 total adverse event reports across all supplement categories. Data not available on side effects specific to this product. High doses of folate can mask a vitamin B12 deficiency [NIH ODS]. Calcium, a related mineral, can cause constipation and nausea at high intakes [NIH ODS].

Our recommendation

Start with one capsule daily. For most adults, 800 mcg is a standard supplemental dose. Choose this form if you have trouble converting folic acid. Check with your doctor if you take methotrexate or anticonvulsants [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide