Product Label

Pure Encapsulations B12 Liquid

Brand: Pure Encapsulations · Form: LIQUID, SUPPLEMENT FORM [E0165]

Our assessment

The evidence shows that Pure Encapsulations B12 Liquid is a supplement designed to deliver vitamin B12, but our assessment is based on the ingredient data provided for calcium, which is listed in the product's ingredient profile. For the specific benefits of vitamin B12, data is not available in the provided information. Based on the calcium data, this product may support bone density and mineral deposition as well as muscle relaxation and nerve signaling [NIH ODS]. You should be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

How it works

Think of the calcium in this formulation as a structural support — it contributes to bone mineralization by helping deposit minerals into your bone matrix, and it also plays a role in neuromuscular relaxation, which supports proper muscle function and nerve signaling [NIH ODS]. This mechanism is critical for maintaining strong bones and healthy muscle contractions throughout your body.

Safety profile

The FDA has received a total of 592,059 adverse event reports across all supplement categories, though specific report counts for this product are not available. Some research suggests that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS].

Our recommendation

Our recommendation is to use this product with caution if you take any medications that interact with calcium, particularly bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, or phenytoin [NIH ODS]. You should avoid exceeding recommended doses to prevent the risks associated with high calcium levels in the blood and urine [NIH ODS]. For specific guidance on vitamin B12 dosing and benefits, data is not available in the provided information, so please consult your healthcare provider for personalized advice.

AI-assisted analysis. Data sourced from NIH DSLD.

Supplement Facts

BrandPure Encapsulations
Serving Size
Contents30.0 mL 1.0 fl. Oz.
Market StatusOff Market

How to Read This Label

Supplement labels contain several key sections regulated by the FDA:

  • Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
  • Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
  • % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
  • Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
  • Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide

Original Label

View Full DSLD Label (PDF)

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