Pure Encapsulations Melatonin 20 mg
Brand: Pure Encapsulations · Form: CAPSULE [E0159] On Market
Our assessment
Our assessment: The evidence shows that a 20 mg melatonin supplement is a very high dose, far exceeding what is typically needed for sleep support. Data on this specific product is limited, but we can provide guidance based on general supplement safety principles. You should be cautious with this dosage, as most adults require only 0.5 mg to 5 mg for sleep.
How it works
Melatonin is a hormone your body naturally produces to regulate your sleep-wake cycle. Think of it as a darkness signal — it tells your brain it is time to prepare for sleep. While data on the specific mechanism for this 20 mg dose is not provided, high doses may have effects beyond sleep, such as influencing immune function and antioxidant activity. Data not available for a specific mechanism at this dosage.
Safety profile
Safety data for this specific product is not available. However, the FDA has received a total of 592,059 adverse event reports across all dietary supplements. Side effects for melatonin in general can include headache, dizziness, and drowsiness the next day. At 20 mg, you are at a higher risk for these effects. Data not available for side effect report counts for this specific product. [FDA data]
Our recommendation
Our recommendation: Start with a much lower dose, typically 1 mg to 3 mg, taken 30 to 60 minutes before bedtime. A 20 mg dose is considered very high and is generally not recommended for routine sleep support without guidance from a healthcare provider. If you choose to use this product, consult your doctor first, especially if you are taking other medications or have a health condition. Data not available for specific dosing guidance for this product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Pure Encapsulations |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide