Pure Encapsulations Melatonin-SR
Brand: Pure Encapsulations · Form: CAPSULE [E0159] On Market
Our assessment
The evidence shows that this product contains melatonin, but the data provided does not include specific information about melatonin. Our analysis must rely strictly on the calcium data provided for this formulation. For calcium, the data supports its role in bone health, but we cannot confirm the effectiveness or safety of the melatonin component based on the available information.
How it works
If this product contains calcium, think of it as a structural support — it supports bone density and mineral deposition through bone mineralization. It also aids neuromuscular relaxation by supporting muscle relaxation and nerve signaling [NIH ODS]. For the melatonin-SR component, specific mechanism data is not available in the provided data.
Safety profile
FDA received 592,059 adverse event reports across all supplement categories, but specific report counts for this product are not available. For calcium, side effects include constipation, nausea, weight loss, extreme tiredness, and frequent need to urinate [NIH ODS]. High calcium levels can cause poor muscle tone, poor kidney function, low phosphate levels, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. High calcium intakes might also increase the risk of heart disease and prostate cancer [NIH ODS].
Our recommendation
Start by consulting your healthcare provider before taking this supplement, as specific melatonin data is not available for a full safety assessment. If you are using this for calcium, be aware that calcium can reduce the absorption of certain medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data not available for specific dosing recommendations for this product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Pure Encapsulations |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide