AOR Advanced Orthomolecular Research Advanced Advanced Magnesium Complex

Our assessment

The evidence shows that this product contains calcium, a mineral essential for bone health and nerve function. However, the data indicates that calcium supplementation comes with notable risks that you should consider carefully before use [NIH ODS].

How it works

Calcium supports your body in two key ways: it helps with bone mineralization, which is the process of building and maintaining bone density, and it promotes neuromuscular relaxation, which supports proper muscle function and nerve signaling [NIH ODS].

Safety profile

Data not available on specific side effects for this product. However, the FDA has received a total of 592,059 adverse event reports across all supplement categories [FDA data]. Regarding calcium specifically, some research suggests that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Given the potential risks associated with high calcium intake, you should not take this supplement without first consulting your healthcare provider. If you do use it, monitor your total calcium intake from all sources, including food and other supplements, and be aware of possible interactions with any medications you take [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide