AOR Advanced Orthomolecular Research Advanced Ovarian Health

Our assessment

The evidence shows that this product contains calcium, a mineral essential for bone health. For you, the key question is whether you need additional calcium beyond what you get from your diet. Our assessment: this supplement is appropriate only if you have a confirmed dietary gap, as excessive intake carries real risks [NIH ODS].

How it works

Think of calcium as a structural building block for your skeleton. It supports bone mineralization and density, and it also plays a role in neuromuscular relaxation and nerve signaling [NIH ODS]. Your body maintains a tight balance of calcium in your blood, pulling from bone stores if your diet is low.

Safety profile

Data not available for this specific product. However, based on the ingredient calcium, high intakes might increase the risk of heart disease and prostate cancer. Very high levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. The FDA received 592,059 total adverse event reports across all supplements, though specific report counts for calcium alone are not provided [FDA data].

Our recommendation

Do not start this supplement without first reviewing your total calcium intake from food and any other supplements. Most adults need 1,000–1,200 mg daily from all sources combined. Because calcium can reduce absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin, take it separately from these drugs [NIH ODS]. We recommend getting your calcium from food first, and only using a supplement if a healthcare provider confirms you need it.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide