Pure Encapsulations Folate 5,000
Brand: Pure Encapsulations · Form: CAPSULE [E0159]
Our assessment
The evidence shows that this product provides a very high dose of folate. Our assessment: for most people, 5,000 mcg of folate is far above the standard RDA and is typically reserved for specific medical conditions like treating megaloblastic anemia or supporting pregnancy in those with a known deficiency. You should only use this dose under the guidance of a healthcare provider. Data on the specific ingredient calcium is provided, but not for folate itself, so we must rely on general principles. Data not available for folate-specific benefits from the provided sources.
How it works
Folate acts as a master regulator of cell division and DNA synthesis. The calcium data provided describes a mechanism for bone mineralization: "Bone mineralization: Supports bone density and mineral deposition; Neuromuscular relaxation: Supports muscle relaxation and nerve signaling" [NIH ODS].
Safety profile
FDA received 592,059 total adverse event reports for all supplements combined. Data not available for side effects specific to this product or folate at this dose. General calcium safety data notes: "High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease" [NIH ODS] [FDA data].
Our recommendation
We recommend you do not take this high dose of 5,000 mcg folate without a specific diagnosis from your doctor. Most adults need only 400 mcg daily. Start with a standard multivitamin or a lower-dose supplement and get your blood levels checked before using this product. Data not available for a specific recommended dose for this product from the provided sources [NIH ODS] [FDA data].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Pure Encapsulations |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide