Product Label

Pure Encapsulations Adenosyl/Hydroxy B12

Brand: Pure Encapsulations · Form: CAPSULE [E0159]

Our assessment

The evidence shows that the primary ingredient in Pure Encapsulations Adenosyl/Hydroxy B12 is calcium, based on the data provided. Our assessment: calcium is a critical mineral for bone health, but you should be aware of its safety profile and potential interactions before adding this supplement to your routine [NIH ODS].

How it works

Calcium acts as a master regulator for your body’s structural and nervous systems. It supports bone mineralization and density, and it also helps with neuromuscular relaxation and nerve signaling [NIH ODS]. Think of it as the key ingredient your body uses to keep your skeleton strong and your muscles functioning smoothly.

Safety profile

Data not available for this specific product’s adverse events. However, based on the FDA’s total adverse event database, there are 592,059 reports across all supplements. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer. Very high blood levels can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of medications such as bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Data not available to confirm the exact dose of calcium in this product, so you should check the label carefully. If you are taking any of the medications listed above, take this supplement at least two hours apart from them. Start with a low dose and monitor for digestive discomfort. We recommend discussing your calcium intake with your doctor, especially if you have a history of kidney stones or heart disease [NIH ODS].

AI-assisted analysis. Data sourced from NIH DSLD.

Supplement Facts

BrandPure Encapsulations
Serving Size
Contents90.0 Capsule(s)
Market StatusOff Market

How to Read This Label

Supplement labels contain several key sections regulated by the FDA:

  • Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
  • Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
  • % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
  • Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
  • Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide

Original Label

View Full DSLD Label (PDF)

Similar Products from Pure Encapsulations