Pure Encapsulations B12 Folate
Brand: Pure Encapsulations · Form: CAPSULE [E0159]
Our assessment
The evidence shows that this supplement combines two nutrients, but the data provided focuses specifically on calcium, not the B12 and folate in this product. For calcium, the data is clear: it supports bone density and nerve signaling [NIH ODS]. However, without specific data on B12 and folate from the provided sources, we cannot assess their effects here. You should know that calcium is essential, but it comes with important safety considerations [NIH ODS].
How it works
Think of calcium as a structural builder and signaler. It works through bone mineralization, helping deposit minerals to maintain strong bone density [NIH ODS]. It also supports neuromuscular relaxation, meaning it helps your muscles relax and your nerves send proper signals [NIH ODS]. These roles are critical for daily function, from moving your body to maintaining a steady heartbeat.
Safety profile
Safety data from the FDA shows a total of 592,059 adverse event reports across all supplements, though specific numbers for this product are not available [FDA data]. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. Very high levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Data not available for B12 and folate specific to this product, so we cannot make a complete recommendation. For calcium, you should be cautious about total intake from all sources, as high levels carry significant risks [NIH ODS]. If you take medications like antibiotics or thyroid hormone, separate calcium intake by at least two hours [NIH ODS]. Always consult your pharmacist or doctor before starting this supplement, especially given the potential for serious side effects and drug interactions [NIH ODS] [FDA data].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Pure Encapsulations |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide