Pure Encapsulations Folate 5,000 Plus
Brand: Pure Encapsulations · Form: CAPSULE [E0159] On Market
Our assessment
The evidence shows that this product contains 5,000 mcg of folate, a dose well above the standard RDA. While folate is essential for cell growth and red blood cell formation, the high dose in this supplement is typically intended for specific medical needs, such as addressing a known deficiency or supporting a high-risk pregnancy. For general use, this level may be unnecessary and could mask a vitamin B12 deficiency [NIH ODS].
How it works
Think of folate as a building block for your body’s genetic material. It is crucial for DNA synthesis and repair, and it works alongside vitamin B12 to produce healthy red blood cells. This specific form, often methylfolate, is the active form your body can use immediately without needing to convert it [NIH ODS].
Safety profile
Data not available for this specific product's side effects. However, the FDA has received 592,059 total adverse event reports across all dietary supplements, though this number is not specific to this product [FDA data]. High doses of folate, generally above 1,000 mcg, can sometimes cause side effects such as stomach upset, sleep disturbances, or skin reactions. More critically, high folate intake can hide a vitamin B12 deficiency, which can lead to permanent nerve damage if left untreated [NIH ODS].
Our recommendation
Our assessment: Do not take this supplement unless a healthcare provider has specifically recommended a 5,000 mcg dose for a diagnosed condition. For most adults, a standard multivitamin or lower-dose folate supplement (400-800 mcg) is sufficient. If you are considering this product, you should first have your blood levels of both folate and vitamin B12 checked by a doctor [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Pure Encapsulations |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide