Pure Encapsulations Melatonin 20 mg
Brand: Pure Encapsulations · Form: CAPSULE [E0159] On Market
Our assessment
The evidence shows that a 20 mg dose of melatonin is significantly higher than what is typically studied or recommended. While melatonin is a well-known supplement for sleep support, this specific product contains a very high potency that may not be appropriate for general use. Data on this specific dosage is not available from the provided sources, and the product formulation is not detailed in the provided data.
How it works
Melatonin is a hormone that your body naturally produces to regulate your sleep-wake cycle, acting as a master regulator of your internal clock. While this product contains melatonin, the specific mechanism of action for a 20 mg dose is not detailed in the provided data. For context, the mineral calcium, which is not in this product, supports bone mineralization and neuromuscular relaxation [NIH ODS].
Safety profile
Data not available for this specific product. The FDA received a total of 592,059 adverse event reports across all dietary supplements, but no specific side effects or report counts are provided for this melatonin product [FDA data]. High doses of other supplements, like calcium, can cause serious side effects including poor muscle tone, nausea, and abnormal heart rhythms [NIH ODS].
Our recommendation
Our assessment is that a 20 mg dose of melatonin is very high. We recommend starting with a much lower dose, typically 0.5 to 5 mg, taken 30 to 60 minutes before bed. Always consult your doctor before using a high-dose supplement like this, especially if you take any medications, as calcium supplements can reduce the absorption of certain drugs like levothyroxine and some antibiotics [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Pure Encapsulations |
|---|---|
| Serving Size | |
| Contents | 180.0 Capsule(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide