Solaray Magnesium Glycinate 400 mg

Our assessment

The evidence shows that Solaray Magnesium Glycinate 400 mg is a supplement designed to support muscle relaxation and nerve signaling. However, based on the data provided, the active ingredient listed is calcium, not magnesium. Our assessment is that you should verify the label carefully, as the data indicates this product contains calcium, which has a specific safety profile and interactions you need to be aware of [NIH ODS].

How it works

Think of calcium as a structural and signaling mineral. It supports bone mineralization and density, and it helps your muscles relax and your nerves transmit signals properly [NIH ODS]. For calcium to work effectively, your body also needs adequate amounts of vitamin D and magnesium, though the specific magnesium content of this product is not provided in the data.

Safety profile

The FDA has received a total of 592,059 adverse event reports across all supplements, but specific report counts for this product are not available. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer. High levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data on side effects specific to this product is not available [FDA data].

Our recommendation

Given the data discrepancy—where the product is named "Magnesium Glycinate" but the ingredient data provided is for calcium—our recommendation is to first confirm the actual ingredient list on the product label you have. If it is a calcium supplement, start with a low dose and take it with food to improve absorption. Be aware of the potential medication interactions listed above. For specific dosing guidance, consult with your healthcare provider, as the exact RDA for you may vary [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide